Capsule endoscopy: The ultimate disposable camera

Swallow this camera; watch what happens in your small intestine

It’s hard to believe any procedure could be a patient’s favorite, particularly when it comes to gastrointestinal procedures. But that’s exactly what a capsule endoscopy has become for patients who need it to diagnose digestive health issues.

The procedure involves swallowing a tiny camera the size of a jellybean. The camera travels down past the stomach and into the small intestine, the organ responsible for breaking your sandwich down into carbohydrates, proteins and fat.

Once there, the camera takes photos of your small intestine — 50,000 to 60,000 digital images — and the shots are transmitted into a recorder worn in a pouch strapped around your waist.

Images are then downloaded onto a computer.

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How changes in gut bacteria boost the growth of a common hospital-acquired infection

Nature study reveals shifts in the gastrointestinal metabolome that facilitate C. difficile infection

Antiobiotic-induced shifts in bacterial makeup allow C. difficile to grow.

Antibiotic-induced shifts in bacterial makeup allow C. difficile to grow.

One of the most common antibiotic-related illnesses, Clostridium difficile, also known as “C. diff,” poses a threat to thousands of Americans hospitalized each year. While most hospital-acquired infections are declining, C. diff is on the rise and causes diarrhea linked to 14,000 American deaths each year.

Major risk factors for getting this infection include staying in the hospital and taking antibiotics.

A new study by the University of Michigan Medical School reveals how antibiotics not only change the bacterial makeup of the gut but also foster the availability of metabolites, which C. difficile can use for germination and growth.

“The findings in our paper are not only vital to the development of new-targeted therapeutics for combatting C. difficile infection but could aid in understanding other gut inflammatory and metabolic diseases, including diabetes, obesity and inflammatory bowel disease, where changes in the gut microbiome could be intimately related to the chemical and nutrient environment,” says lead author Casey Theriot, Ph.D., Research Investigator in the Division of Infectious Diseases at the University of Michigan Medical School.

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